Multiplicity of microbiota species is characteristic of the GI microbiome in healthy individuals, and a loss in species has adverse effects. Dietary diversity and taking a variety of probiotic species and strains are methods that help support a healthy microbiome. ProbioMax 350 DF provide 18 different strains belonging to 13 different species of three different genera. For consumer convenience, these formulas are available as a powder at a dose of 350 CFUs per stick pack. The HOWARU and FloraFIT strains that comprise these formulas are stable, proven, and trusted worldwide.
 

Featured Strains: Bifidobacterium lactis HN019® and Lactobacillus
rhamnosus HN001®
B lactis HN019® and L rhamnosus HN001® have been studied extensively in vitro and in vivo (in animals and humans) to establish beneficial effects and safety. In human research, B lactis HN019® significantly decreased mean whole-gut transit time in adults compared to placebo.Supplementation also had a positive effect on functional GI symptoms, as were self-reported by patient surveys. In a randomized, double-blind, placebo-controlled human dietary intervention study in subjects 60 or more years of age, supplementary HN019® resulted in desirable changes in the intestinal microflora, including significant increases in bifidobacteria and lactobacilli. HN019® has also shown promising effects on parameters of cardiovascular and metabolic health. Compared with baseline and control group values, individuals taking 27 billion CFU had a significant reduction in body mass index, significant improvements in cholesterol and low-density lipoprotein metabolism, and significant decreases in tumor necrosis factor-alpha and interleukin-6. In a three-week study, individuals consuming low-fat/low-lactose milk supplemented with HN019® or HN001® showed increased immune activity when compared to a milk-alone run in. These increases were significantly correlated with age; that is, subjects older than 70 years experienced significantly greater improvements than those under 70 years. Researchers suggest that these results demonstrate the ability of HN019® and HN001® to combat some of the deleterious effects of immunosenescence on cellular immunity. Animal studies demonstrate the ability of HN001® to support natural and acquired immunity as well as promote resistance. More recently, human studies have demonstrated HN001®’s protective effect on skin health in genetically susceptible individuals.

Clinical Applications
» Supports a Healthy Microbiome*
» Replenishes Good Bacteria in the Gut*
» Supports the Natural Immune Response*
» Supports Lactose Digestion*
» Supports Bowel Regularity*

ProbioMax ® 350 DF feature a diverse
blend of HOWARU® and FloraFIT ® probiotic strains to support a healthy
gut microbiome. Each strain is well-researched and identity-verified
and has been genetically characterized and properly classified for your
safety and assurance. These strains were not only selected for their
health benefits and complementary actions but also for their viability and
stability. To protect the bacteria from light and moisture, opaque and foillined
packaging is utilized for both formulas.

Other Strains in ProbioMax 350 DF and ProbioMax Complete DF Have
Demonstrated Probiotic Effects in Either In Vitro or In Vivo Research:
• Cause the development of inhibition zones around Clostridium difficile,
Salmonella typhimurium, Staphylococcus aureus, Escherichia coli, and
Listeria monocytogenes in agar assays
• Populate vaginal tissue
• Induce moderate maturation and activation of dendritic cells
• Degrade oxalates
• Increase IgA and IgG responses
• Reduce levels of E coli and enterococcus after antibiotic therapy
• Help increase and recover numbers of intestinal lactobacilli and/or
bifidobacteria
• Promote well-being in relation to intestinal cytokine production
• Improve gastrointestinal health and well-being when under challenge
• Help maintain upper respiratory health
• Alter the fecal microbiota in obese subjects
• Maintain healthy fluid balance and integrity of intestinal wall
• Support intestinal barrier function

Genetic Testing, Acid and Bile Tolerance, Adhesion
The lactic acid-producing strains in these formulas have a history of safe
consumption and, based on testing, have excellent probiotic potential.
Each bacterium has been genetically characterized and properly classified
by independent labs. The organisms have demonstrated tolerance to low
pH conditions (hydrochloric acid and pepsin at pH3 for one hour at 37°C),
tolerance to bile at concentrations existing in the duodenum, and the ability
to adhere to human epithelial cell lines (Caco-2 and HT-29). Adhesion is
thought to be an important factor affecting these bacteria’s length of time in the intestines, their ability to modulate immune function, and their ability to take up intestinal “real estate” in competition with other organisms.
Many of the strains have had additional studies performed, which include
testing for the following:

Competitive Inhibition – The ability of probiotics to maintain a healthy microbial balance in the gut is unquestionably important to its usefulness. Probiotics produce inhibitory compounds that limit the growth of other organisms, they compete with other organisms for adhesion sites and nutrients, and they inhibit the production of toxins, among other actions.*
Cytokine and Immune Modulation – Microbiota are key elements in the body’s defense system. Cytokines regulate immune system function, and the included strains have demonstrated the ability to upregulate or downregulate various cytokines.
Antibiotic Resistance – Antibiotic susceptibility patterns are an important means of indicating the potential of an organism to be readily inactivated by antibiotics used in human therapy. Importantly, acquired antibiotic resistance or antibiotic resistance transfer have not been detected in any of these strains.

Best Way To Consume ProbioMax 350 DF:

I recommend inoculating 32 oz of raw goat or cows milk with 1 sachet of ProbioMax 350 DF and allow to incubate in your oven with the oven light on only. Crack the door of your oven open with a book, so that the temperature stays around 100 degrees F. In 16 to 24 hours you'll have yogurt. For best results, consume this daily for 30 to 90 days. For those with constipation or inflammation of your colon, then once per week using an enema syringe bulb, insert 8 oz of this yogurt into your rectum and hold for 15 minutes before expelling. Lubricate the enema tip with Silica Gel or butter or olive oil.

I also recommend you soak and start the germination process in either sunflower seeds, pumpkin seeds, almonds, pecans or macadamia nuts, or whatever nut or seed you desire. Then after the 3 days of rising and germinating, you'll puree 2-4 cups of these soaked nuts or seeds into water, with 1 sachet of ProbioMax 350 DF. Pour into a 32 or 64 oz mason jar and culture in the warmth of your oven with the oven light on for 4 hours only. These seed and nut yogurts ferment quickly, so 4 hours is all you need.

Consuming this nut or seed yogurt is fantastic to restore healthy bowel movements and improve your gut microbiome.

ProbioMax® 350 DF Supplement Facts
Serving Size: 1 Stick Pack (about 4.5 g)
Servings Per Container: 15
Amount Per Serving %Daily Value
Calories 15
Total Carbohydrate 3 g 1%†
Protein 1 g
Sodium 5 mg <1%†
Lactobacillus acidophilus La-14® 625 mg (125 Billion CFU‡)
Bifidobacterium lactis Bl-04® 200 mg (100 Billion CFU‡)
Lactobacillus bulgaricus Lb-87™ 100 mg (5 Billion CFU‡)
Bifidobacterium longum subsp. Infantis Bi-26™ 100 mg (5 Billion CFU‡)
HOWARU® Bifido (Bifidobacterium lactis HN019®) 83.3 mg (25 Billion CFU‡)
Lactobacillus plantarum Lp-115® 50 mg (20 Billion CFU‡)
Bifidobacterium longum Bl-05™ 50 mg (5 Billion CFU‡)
Bifidobacterium bifidum Bb-06™ 50 mg (5 Billion CFU‡)
HOWARU® Rhamnosus (Lactobacillus rhamnosus HN001®) 33.3 mg (15 Billion CFU‡)
Lactobacillus rhamnosus Lr-32® 25 mg (5 Billion CFU‡)
Lactobacillus brevis Lbr-35™ 25 mg (5 Billion CFU‡)
Lactobacillus gasseri Lg-36™ 25 mg (5 Billion CFU‡)
Lactobacillus casei Lc-11® 16.67 mg (5 Billion CFU‡)
Lactobacillus salivarius Ls-33® 16.67 mg (5 Billion CFU‡)
Bifidobacterium breve Bb-03™ 16.67 mg (5 Billion CFU‡)
Lactococcus lactis Ll-23™ 16.67 mg (5 Billion CFU‡)
Streptococcus thermophilus St-21™ 12.5 mg (5 Billion CFU‡)
Bifidobacterium bifidum/Bifidobacterium lactis Bb-02™ 11.1 mg (5 Billion CFU‡)
Other Ingredients: Potato maltodextrin, calcium silicate, and magnesium stearate.
‡Colony-Forming Units
††Formulated with 650 billion CFU‡ at time of manufacture
HN001® and HN019® are registered trademarks of Fonterra™ Limited and are licensed to DuPont Nutrition Biosciences.
DIRECTIONS: Dissolve the contents of one stick pack (350 billion CFU‡)†† into 2-4oz of pure water and consume once daily, or take as directed by your healthcare practitioner.